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Hyaluronidase and Filler Dissolving

Hyaluronidase is an enzyme that breaks down hyaluronic acid. It works as an "eraser" for hyaluronic acid fillers: it helps remove excess volume, asymmetry, migrated gel or lumps after an unsuccessful lip or facial correction. At UKRMED Cosmetology, the treatment is carried out by cosmetologist Nataliia Tarhonska after an examination and a check of which product was injected and when.

Hyaluronidase Kyiv — cosmetologist consultation

The doctor will assess your tissues and explain whether dissolving is needed and how much.

How hyaluronic acid filler dissolving works

Most lip and facial fillers are made of cross-linked hyaluronic acid. The enzyme breaks its molecules apart, and the body clears the remnants naturally. The effect is visible within a day, and the final result once swelling subsides.

Important: the enzyme works only on hyaluronic acid fillers. Calcium hydroxylapatite products (Radiesse), poly-L-lactic acid and permanent fillers are not dissolved. If you do not know the product name, tell the doctor — filler type cannot be judged by eye.

When filler removal is needed

  • excessive or unnatural volume;
  • asymmetry after a correction;
  • gel migrating beyond the treated area, such as a "shelf" above the lip;
  • lumps and irregularities;
  • a bluish tint under thin skin (Tyndall effect);
  • preparation for a new, more accurate correction;
  • emergency treatment if filler enters a blood vessel.

Lip filler correction

The most common request is dissolving lip filler after over-augmentation or gel migration. Removal can be partial — only the excess in one area — or complete. If filler was injected several times, a staged approach may be needed. Once the tissues recover, usually after a few weeks, a subtle lip filler treatment can be planned again.

Safe filler removal

A 2021 UK expert guideline on the safe use of hyaluronidase stresses that the enzyme is usually well tolerated, but allergic reactions are possible. The risk is higher in people allergic to wasp and bee stings, so be sure to tell the doctor. A skin test can be done beforehand if needed.

A separate guideline by the same authors on vascular complications of fillers recommends giving hyaluronidase as soon as possible and in a sufficient dose if a blocked vessel is suspected. That is why every doctor who uses fillers must keep the enzyme on hand.

The procedure

  1. Consultation. The doctor checks the product, volume and date of injection, allergies and medicines.
  2. Skin test — if indicated.
  3. Injection. The enzyme is placed with a fine needle or cannula precisely into the filler.
  4. Review. The doctor assesses the result and plans a repeat session if needed.

Filler dissolving at UKRMED

Call us or leave a request on the website.

Aftercare

Swelling, redness and tenderness may last one to two days. Do not massage your lips or try to "spread" the product. Resume exercise, saunas, facial massage and new injections as the doctor advises. If pain or swelling increases or the skin changes colour, contact the doctor immediately.

Contraindications

Allergy to hyaluronidase, acute inflammation or infection in the area, pregnancy and breastfeeding (except emergencies — the doctor decides).

Signs of a vascular complication after filler

Contact a doctor immediately if, after a filler treatment, you notice:

  • sharp pain out of proportion to the procedure;
  • blanching of the skin, followed by a mottled, bluish or dark pattern;
  • blisters in the treated area a few days later;
  • any change in vision or eye pain.

This is an emergency. The guideline on vascular occlusion recommends giving hyaluronidase as soon as possible and in a sufficient dose — the outcome depends on speed.

Why problems occur after fillers

The most common causes are too much volume in one session, the wrong product for the area, injection that is too superficial, and repeated top-ups without accounting for leftover gel. That is why it is important to know what was injected and when before any new treatment.

Prices at UKRMED

Service Price
Filler dissolving — Pb Serum UAH 2,000

If staged dissolving is needed, the total depends on the number of sessions.

We'll fix an unsuccessful correction

Book an examination — the doctor will suggest a gentle solution.

Sources

  1. Murray G., Convery C., Walker L., Davies E. Guideline for the Safe Use of Hyaluronidase in Aesthetic Medicine, Including Modified High-dose Protocol. J Clin Aesthet Dermatol, 2021. https://pubmed.ncbi.nlm.nih.gov/34840662/
  2. Murray G., Convery C., Walker L., Davies E. Guideline for the Management of Hyaluronic Acid Filler-induced Vascular Occlusion. J Clin Aesthet Dermatol, 2021. https://pubmed.ncbi.nlm.nih.gov/34188752/
  3. U.S. Food and Drug Administration. Dermal Fillers (Soft Tissue Fillers). https://www.fda.gov/medical-devices/aesthetic-cosmetic-devices/dermal-fillers-soft-tissue-fillers
Specialists in the field of Hyaluronidase
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FAQ

Yes, if it is hyaluronic acid filler. Gel remnants can persist longer than expected, and the enzyme breaks them down.

Yes, with an examination and a check for allergies. Temporary swelling and redness are possible; allergic reactions are rare.

Hyaluronic acid filler will, though several sessions are sometimes needed. Other filler types are not dissolved.

The enzyme acts on hyaluronic acid, and your own quickly recovers, so the natural volume of your lips does not decrease.

Usually after two to four weeks, once swelling has fully subsided.

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